GHK-Cu
The Copper-Powered Peptide for Healing, Regeneration & Youthful Vitality
What is GHK-Cu?
GHK-Cu is a powerful copper-bound tripeptide composed of glycine, histidine, and lysine, naturally occurring in human plasma and tissues. When bound to copper (Cu²⁺), it becomes GHK-Cu (Copper Tripeptide-1)—a bioactive molecule known for its ability to stimulate tissue repair, reduce inflammation, and enhance collagen production.
This injectable form of GHK-Cu is formulated for advanced research applications where systemic or localized regenerative effects are desired. It offers enhanced bioavailability, bypasses the skin barrier, and delivers the peptide directly into circulation or target tissue.
How Does GHK-Cu Work?
GHK-Cu acts as a signaling molecule, activating repair pathways and gene networks responsible for collagen synthesis, antioxidant defense, and inflammatory modulation.
Mechanism of Action:
- Binds to cell surface receptors to initiate tissue remodeling
- Activates superoxide dismutase (SOD) and other antioxidant enzymes
- Promotes expression of genes related to skin structure, healing, and immunity
- Reduces NF-κB activity to suppress pro-inflammatory responses
Key Benefits of GHK-Cu
💉 Enhanced Delivery & Performance
- Directly absorbed into circulation or targeted tissues
- Allows precise dosing control
- Avoids degradation by topical enzymes or skin barrier limitations
🧬 Cellular Regeneration & Healing
- Accelerates wound healing and scar reduction
- Promotes angiogenesis and fibroblast activity
- Rebuilds collagen, elastin, and glycosaminoglycans
🔥 Anti-Inflammatory & Antioxidant
- Reduces oxidative stress markers and tissue inflammation
- Modulates TNF-α, IL-6, and related cytokines
- May support joint and muscle recovery
🌿 Aesthetic & Skin Benefits
- Improves skin tone, elasticity, and hydration
- Softens fine lines, wrinkles, and discoloration
- Often paired with microneedling or aesthetic procedures
Suggested Dosage & Protocol
Injectable GHK-Cu is intended for research use only. Dosage should be based on goals and target systems.
Common Dosing:
- 100mcg to 300mcg per injection, once or twice daily
- Administer subcutaneously (SC) for systemic support
- Intramuscular (IM) or localized SC for targeted injury sites
Cycle Duration:
- 2–6 weeks, with rest periods based on research outcomes
- Can be repeated monthly or quarterly for long-term protocols
GHK-Cu vs Other Peptides
Feature | GHK-Cu Injectable | BPC-157 | TB-500 |
---|---|---|---|
Main Action | Collagen, repair, antioxidant | GI, tendon, vascular repair | Muscle, cardiac, connective tissue |
Administration | SC or IM injection | SC, oral, IM | SC or IM |
Wound Healing | Excellent | Excellent | Moderate |
Skin Regeneration | Strong | Mild | Minimal |
GHK-Cu shines in skin regeneration, cosmetic rejuvenation, and long-term tissue maintenance protocols.
Safety Profile of Injectable GHK-Cu
GHK-Cu has an excellent safety record in topical and injectable research. As a naturally occurring molecule, it is well tolerated, with minimal risk of systemic disruption.
Safety Highlights:
- Non-toxic, non-immunogenic
- Does not raise IGF-1 or hormone levels
- Safe for long-term cycles when used properly
Rare Side Effects:
- Mild injection site redness or irritation
- Temporary metallic taste (rare)
- Slight fatigue or flu-like symptoms in sensitive individuals
Reference:
- Pickart L. “The Human Tripeptide GHK-Cu and Tissue Regeneration.” J Biomater Sci Polym Ed., 2008. https://pubmed.ncbi.nlm.nih.gov/18588407/
Ideal Stack Partners
Injectable GHK-Cu plays well with other regenerative peptides:
- BPC-157 – for tendon and soft tissue synergy
- TB-500 – for systemic tissue repair and inflammation
- Epithalon – for aging-related support and DNA repair
- GHK (Basic) – for layering copper-free topical protocols
Storage Guidelines
- Store lyophilized GHK-Cu in the refrigerator at 2–8°C
- After reconstitution with bacteriostatic water, refrigerate and use within 14–30 days
- Protect from light and do not shake vigorously during mixing
Is GHK-Cu Injectable Right for Your Research?
If your focus includes advanced skin repair, wound healing, or oxidative damage mitigation, GHK-Cu injectable offers a high-purity, targeted option. Its bioactive potential extends from cosmetic science to regenerative biology, making it one of the most versatile research peptides available.
Final Thoughts
Injectable GHK-Cu is a cornerstone peptide for any protocol focused on rebuilding, regenerating, or restoring. With powerful biological effects and minimal side effects, it deserves a starring role in serious repair and rejuvenation studies.
Lab of RAD offers research-grade GHK-Cu injectable powder for elite experimental applications.
⚠️ FDA Disclaimer
This content is provided for educational and research purposes only. GHK-Cu has not been evaluated or approved by the U.S. Food and Drug Administration (FDA). It is not intended to diagnose, treat, cure, or prevent any disease. Consult a licensed medical professional before conducting any research protocol.
Lab of RAD peptides are intended for laboratory research use only and are not for human consumption.