hGH Fragment 176-191

Fat Loss Without the Side Effects of Growth Hormone

What is hGH Fragment 176-191?

hGH Fragment 176-191 is a synthetic peptide fragment derived from the C-terminal region of human growth hormone (hGH). Specifically, it comprises amino acids 176 to 191 of the full 191-amino acid hGH molecule. While it is not the complete hormone, this fragment has been shown to retain—and even amplify—the fat-burning and metabolic effects of hGH without the adverse side effects like insulin resistance or IGF-1 elevation.

This makes hGH Frag 176-191 a compelling candidate in peptide research targeting fat loss, obesity management, and body composition optimization.

How Does hGH Fragment 176-191 Work?

Unlike full-length growth hormone, which has broad systemic effects, hGH Frag 176-191 selectively modulates fat metabolism. It stimulates lipolysis (the breakdown of stored fat) while simultaneously inhibiting lipogenesis (the formation of new fat cells).

Mechanism of Action:

  • Binds to fat cell receptors to activate fat-burning pathways
  • Increases mitochondrial activity in adipose tissue
  • Does not raise blood sugar or IGF-1 levels
  • Does not stimulate bone, organ, or muscle growth

Key Benefits of hGH Frag 176-191

🔥 Targeted Fat Loss

  • Increases lipolysis and mobilization of stored fat
  • Inhibits lipogenesis even in high-calorie environments
  • Supports visceral fat reduction in clinical trials

💪 Lean Mass Preservation

  • Encourages fat reduction while maintaining muscle mass
  • Ideal for cutting cycles or recomposition research

🩺 No Hormonal Disruption

  • Does not elevate IGF-1 or promote insulin resistance
  • No increase in water retention or joint swelling (unlike hGH)
  • Well tolerated across a wide range of doses

🧪 High Specificity

  • Acts only on adipose tissue receptors, not on muscle or bone
  • Great for researchers studying targeted metabolic modulation

Suggested Dosage & Protocol

Common Dosage:

  • 250mcg to 500mcg per day, divided into 1–2 doses
  • Administered subcutaneously, typically in the abdominal region

Timing:

  • Best used in the morning fasted, pre-workout, or before bed
  • Avoid carbohydrate consumption 60 minutes before and after injection for optimal fat-burning response

Duration:

  • 4–12 week cycles are common in fat loss research protocols

hGH Fragment vs Full hGH

FeaturehGH Fragment 176-191Full hGH (Somatropin)
IGF-1 ElevationNoYes
Fat BurningTargetedGeneralized
Muscle GrowthNoYes
Side EffectsLowModerate to High
Water RetentionMinimalCommon
Blood Sugar ImpactNeutralPossible insulin resistance

Frag 176-191 offers fat-burning benefits without the hormonal baggage of full growth hormone therapy.

Safety Profile of hGH Frag 176-191

hGH Fragment 176-191 is considered very safe in research contexts due to its high specificity and minimal systemic impact.

Reported Safety Insights:

  • Does not affect blood pressure, IGF-1, or glucose levels
  • Non-toxic and non-mitogenic (doesn’t promote unwanted cell growth)
  • Well tolerated even at higher doses

Rare Side Effects:

  • Mild redness or irritation at injection site
  • Slight fatigue or temporary headache in sensitive individuals

Reference:

Storage Instructions

  • Store lyophilized Frag 176-191 at 2–8°C in a light-protected container
  • Once reconstituted, refrigerate and use within 14–30 days
  • Use bacteriostatic water for optimal preservation

Ideal Stack Pairings

hGH Frag 176-191 works best in fat loss or cutting protocols:

  • CJC-1295 (no DAC) – to amplify GH pulses
  • Ipamorelin – for synergistic GH stimulation without appetite stimulation
  • 5-Amino-1MQ – for additional fat metabolism support
  • BPC-157 or AOD9604 – to enhance healing and lipolytic synergy

Is hGH Fragment 176-191 Right for Your Research?

If your research focuses on adipose regulation, body recomposition, or non-hormonal fat modulation, hGH Fragment 176-191 is a highly specific and low-risk compound to study. It is particularly well-suited for those wanting the metabolic benefits of growth hormone without muscle growth or endocrine disruption.

Final Thoughts

hGH Fragment 176-191 offers a focused, research-grade approach to fat loss without the hormonal complexities of full GH therapy. Whether you’re investigating obesity treatment, lipolytic signaling, or metabolic enhancement, this peptide delivers science-backed performance with precision.

Lab of RAD offers high-purity hGH Fragment 176-191 for advanced fat loss and metabolic research.

⚠️ FDA Disclaimer

This content is intended for educational and research purposes only. hGH Fragment 176-191 has not been evaluated or approved by the U.S. Food and Drug Administration (FDA). It is not intended to diagnose, treat, cure, or prevent any disease.

Lab of RAD peptides are for laboratory research use only and are not for human consumption.